Avene is a contemporary dermo cosmetic skincare brand, recommended by healthcare professionals worldwide and is trusted by millions. The thermal spring water source from which avene products derive has been used to care for sensitive skin for over 270 years. A concentrated cream with pure hyaluronic acid 0.2% and niacinamide 6%, which acts on the signs and causes of ageing in vitro test, thanks to niacinamide. Skin feels firmer, and wrinkles appear reduced after use. To use apply morning and or evening to the face, neck and decollete, by itself or following your serum. Avene offers ranges suitable for all skin concerns very sensitive skin, dehydrated, oily and blemish prone, anti ageing, sun protection, dull skin, dry skin, redness prone, and itchy skin. Please note this item is a refill.