Neilmed sinurinse is designed to provide natural sinus relief that effectively relieve allergies and sinus symptoms such as nasal allergies and congestions, sinus pressure and nasal stuffiness, nasal symptoms from flu and cold and nasal dryness with no burning, preservative free and drug free.this pack of 50 refill sachets is designed for use in conjunction with the nielmed sinurinse bottle available for purchase within the nielmed starter kit. P p features p p bull soothing br bull no burning or stinging br bull drug free br bull preservative free br bull patented mixture formula br bull reduces pollen load br bull provides natural relief from symptoms of common cold and flu p p pack contains p p bull 50 sachets of usp grade sodium chloride and sodium bicarbonate mixture br bull educational brochure br bull directions fro use in english p p for best results neilmeds mixture sachets should be used in conjunction with neilmeds 240ml nasal irrigation bottle device. P