Nicotinell lozenge contains nicotine. When you suck the lozenge, the nicotine is slowly released and absorbed through the lining of the mouth. The lozenge can alleviate some of the unpleasant withdrawal effects that frequently occur when giving up smoking, such as cravings and irritability.the lozenge can reduce your desire to smoke and help improve your willpower to resist smoking by providing some of the nicotine previously inhaled.nicotinell lozenge is best suited for those with medium nicotine dependency, and is not recommended for those smoking more than 30 cigarettes per day.