American stop motion animation directed by wes anderson in which future japan sees itself overrun by packs of dogs which are beginning to spread the disease to humans. A mayor's solution is to exile every dog to an island filled with toxic waste and rubbish, where they will live out their days away from civilization. When a young boy is devastated to find his dog is missing, he flies a plane to the island where he enlists the help of its inhabitants to track him down. As the dogs become frustrated with their new home, they formulate a plan to get off the island and back to the mainland. The cast includes the voice talents of bryan cranston, edward norton, bill murray, jeff goldblum and scarlett johansson.